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Updated: Jul 13, 2026

Using a Microfluidics Device for Mechanical Stimulation and High Resolution Imaging of C. elegans
Published on: February 19, 2018
Primed to squeeze: mechanical memory in confined migration
Marine Luciano1, Sylvain Gabriele1
1SYMBIOSE Lab, Research Institute for Biosciences, AdHuCell Platform, CIRMAP, University of Mons (UMONS), Place du Parc, 20, Mons B-7000, Belgium.
Abstract:
Do cells remember past mechanical experiences to prepare for future physical challenges? Holle et al. demonstrate that stiffness priming enhances confined migration through NFATC2-dependent programs. Beyond this specific mechanism, their work supports the emerging concept of mechanical memory as a hierarchy of interconnected cellular states operating across multiple timescales.
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