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Updated: Jul 13, 2026
07:50
Establishment of a Clinic-based Biorepository
Published on: May 29, 2017
A Decade of the YODA Project: Advancing Clinical Trial Data Sharing through Transparency, Independence, and
Erfan Taherifard1, Jessica D Ritchie1, Molly K Willeford1
1Section of General Internal Medicine, Yale School of Medicine, New Haven, CT, USA.
Scientific Data
|July 11, 2026
Summary
The Yale University Open Data Access (YODA) Project facilitates transparent sharing of clinical trial data. This initiative has successfully enabled independent research, leading to numerous peer-reviewed publications and advancing medical knowledge.
Area of Science:
- Clinical Research
- Data Science
- Public Health
Background:
- The Yale University Open Data Access (YODA) Project, established in partnership with Johnson & Johnson since 2014, is an academic-led effort.
- It focuses on promoting independent, transparent, and responsible sharing of clinical trial data.
Purpose of the Study:
- To evaluate the Yale University Open Data Access (YODA) Project's decade-long impact on clinical trial data sharing.
- To assess the accessibility, utilization, and scientific output derived from shared participant-level data.
Main Methods:
- The YODA Project provides access to individual participant-level data and supporting documentation from clinical trials.
- Data access is granted to investigators for independent studies.
- Tracking of data requests, approval rates, time to access, and subsequent publications.
Main Results:
- As of March 31, 2025, data from 482 clinical trials across 86 medical conditions and 49 products were available.
- A total of 485 data requests were submitted, with 95.5% approved.
- Investigators gained data access in a median of 82.5 days, and 30.0% of approved requests led to 165 peer-reviewed articles.
Conclusions:
- The YODA Project demonstrates the successful implementation of a data sharing platform.
- Responsible data sharing promotes transparency, builds trust, and significantly advances clinical research.
- The initiative supports a wide range of scientific inquiries and fosters independent study.
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