A Modified Enhanced Recovery After Surgery Protocol Versus Standard Care in Pediatric Major Gastrointestinal Surgery:

Andi Ade Wijaya Ramlan1, Kshetra Rinaldhy2, Rahendra Rahendra1

  • 1Department of Anesthesiology and Intensive Care, Faculty of Medicine, Universitas Indonesia, Dr. Cipto Mangunkusumo Hospital, Jakarta, IDN.

Cureus
|July 13, 2026
PubMed

Insights

A modified Enhanced Recovery After Surgery (ERAS) protocol improved outcomes for pediatric patients undergoing major gastrointestinal surgery. This approach led to faster mobilization and shorter hospital stays compared to standard care.

Area of Science:

  • Pediatric Surgery
  • Enhanced Recovery After Surgery (ERAS) Protocols
  • Perioperative Care

Background:

  • Pediatric major gastrointestinal surgery often involves prolonged fasting and delayed mobilization, increasing stress and slowing recovery.
  • Enhanced Recovery After Surgery (ERAS) pathways, successful in adults, need adaptation for pediatric populations.
  • Current standard care may not optimize perioperative management for young surgical patients.

Purpose of the Study:

  • To evaluate a modified ERAS protocol against standard care in pediatric patients undergoing major gastrointestinal surgery.
  • To assess the impact of the modified ERAS protocol on key recovery metrics.
  • To determine if pediatric-adapted ERAS pathways improve perioperative outcomes.

Main Methods:

  • Single-blind randomized controlled trial involving pediatric patients (2 months to 5 years) undergoing major gastrointestinal surgery.
  • Randomization into two groups: modified ERAS protocol (n=40) and standard care (n=42).
  • Outcomes measured: time to oral nutrition, mobilization, urinary catheter removal, length of hospital stay, and intraoperative glucose/electrolyte levels.

Main Results:

  • The modified ERAS group showed significantly faster mobilization (p=0.014) and shorter hospital stays (p=0.018).
  • Improved intraoperative glucose stability was observed in the modified ERAS group at later timepoints (p=0.047, p=0.008).
  • No significant differences were found in time to oral nutrition or urinary catheter removal between groups.

Conclusions:

  • A modified ERAS protocol enhances perioperative recovery in pediatric major gastrointestinal surgery.
  • The protocol is associated with earlier mobilization, reduced hospitalization duration, and better glucose control.
  • Adapting ERAS pathways for pediatric patients shows promise for improving surgical outcomes.

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