Related Experiment Video
Updated: Jul 15, 2026
04:12
Roller Microneedle Combined with Tranexamic Acid Solution in Treating Melasma
Published on: January 19, 2024
[Lying needling from Nanjing for malar melasma: a randomized controlled trial]
Xiaofan Zhao1, Youjia Gu1, Jiaqi Man1
1Department of Acupuncture and Moxibustion, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of TCM, Shanghai 200437, China.
Zhongguo Zhen Jiu = Chinese Acupuncture & Moxibustion
|July 13, 2026
Summary
Lying needling from Nanjing effectively treats malar melasma by improving skin condition and quality of life. This traditional acupuncture method demonstrated significant clinical efficacy and safety in a randomized controlled trial.
Area of Science:
- Integrative Medicine
- Dermatology
- Traditional Chinese Medicine
Background:
- Malar melasma is a common skin condition causing facial hyperpigmentation.
- Existing treatments have limitations in efficacy and safety.
Purpose of the Study:
- To evaluate the clinical effectiveness and safety of lying needling, based on the Nanjing (Classic of Difficult Issues), for treating malar melasma.
Main Methods:
- A randomized controlled trial involving 78 patients with malar melasma.
- Comparison between lying needling group and sham acupuncture group over 3 weeks.
- Assessment of melasma area and severity index (MASI), dermatology life quality index (DLQI), and skin temperature.
Main Results:
- Lying needling significantly reduced MASI and improved skin temperature compared to baseline and sham group.
- Both groups showed DLQI improvement, but lying needling showed greater MASI and symptom score reduction.
- Total effective rate for lying needling was 89.5%, significantly higher than the sham group (31.6%).
Conclusions:
- Lying needling from Nanjing is an effective and safe treatment for malar melasma.
- It improves clinical symptoms and enhances patients' quality of life.
- The treatment shows promising results with no reported adverse events.