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Three-Dimensional Morphometric Trajectories Following Lip Lift With or Without Fat Grafting in Facial Feminization
Aesthetic Surgery Journal. Open Forum
|July 14, 2026
Summary
Subnasal lip lifts shorten the philtrum, but some lengthening occurs over time. Early lip volume and surface area gains diminish significantly within two years, with limited long-term retention from fat grafting.
Area of Science:
- Plastic Surgery
- Facial Aesthetics
- 3D Imaging Analysis
Background:
- Subnasal lip lifts are used to address perioral aging.
- Long-term quantitative data on the permanence of subnasal lip lift outcomes are limited.
Purpose of the Study:
- To conduct the first 3D morphometric evaluation of changes after subnasal lip lift with or without autologous fat grafting.
- To analyze the long-term changes and permanence of these procedures over time.
Main Methods:
- Retrospective analysis of 40 facial feminization patients undergoing subnasal lip lift ± fat grafting.
- Standardized 3D VECTRA imaging to measure key facial parameters preoperatively and postoperatively.
- Statistical analysis using t-tests and linear mixed-effects models to assess early changes and longitudinal trajectories.
Main Results:
- Both groups showed significant early philtral shortening and increased upper vermilion surface area.
- Fat grafting resulted in greater early volumetric augmentation, though not statistically significant.
- Philtral shortening showed 43% retention at 24 months, while volume and surface area gains approached zero by 2 years.
Conclusions:
- Subnasal lip lifts cause measurable philtral shortening, with partial relengthening over time.
- Early gains in lip volume and vermilion display significantly decrease by two years.
- Autologous fat grafting provides enhanced early augmentation but limited long-term retention.

