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First Argentine Consensus on the Management of Schizophrenia. Section four. Management of Schizophrenia in Special

Alejo Corrales1, Andrea Abadi2, Gastón Bartoli3

  • 1Magíster en Biología Molecular e Ingeniería Genética, Universidad Favaloro. Docente de la Universidad Nacional de Tucumán (UNT). Presidente del Capítulo de Psiquiatría Genética, Asociación Argentina de Psiquiatras (AAP), Buenos Aires, Argentina. alejocorrales@hotmail.com.

Vertex (Buenos Aires, Argentina)
|July 14, 2026
PubMed

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Summary

This consensus provides comprehensive guidelines for managing schizophrenia in special populations and complex cases. It covers treatment-resistant schizophrenia, youth, perinatal care, older adults, suicide prevention, stigma, and psychosocial rehabilitation.

Area of Science:

  • Psychiatry
  • Clinical Psychology
  • Public Health

Background:

  • Schizophrenia management requires tailored approaches for diverse patient groups.
  • Special populations and complex clinical situations present unique challenges in schizophrenia care.
  • The Argentinian Association of Biological Psychiatry (AAPB) developed this consensus to address these gaps.

Purpose of the Study:

  • To provide an expert review and critical assessment of current evidence for managing schizophrenia in special populations.
  • To offer comprehensive guidelines for complex clinical scenarios, including treatment resistance and high-risk groups.
  • To integrate insights from family associations and address medico-legal aspects.

Main Methods:

  • Critical review of scientific evidence.
Keywords:
treatment-resistant schizophreniaultra-treatment-resistant schizophreniaspecial populationspsychosocial rehabilitationsuicidestigmaperinatal periodolder adultsphysical activityhomelessnessforensic psychiatryfamily caregivers

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  • Expert valuation of available data.
  • Inclusion of perspectives from family associations (AAFE).

    • Main Results:

    • Detailed recommendations for managing treatment-resistant and ultra-resistant schizophrenia.
    • Specific strategies for schizophrenia in children, adolescents, perinatal women, and older adults.
    • Guidance on suicide prevention, stigma reduction, physical activity, psychosocial rehabilitation, and social vulnerability.

    Conclusions:

    • This consensus offers a holistic framework for schizophrenia management across diverse and complex patient profiles.
    • It emphasizes the crucial role of family support and addresses medico-legal considerations.
    • The guidelines aim to improve functional and cardiometabolic outcomes and promote recovery.