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Related Concept Videos

Biofilms01:29

Biofilms

Biofilms are complex communities of microorganisms encased in a self-produced extracellular polysaccharide matrix attached to surfaces. These microbial consortia can include single or multiple species, providing enhanced survival benefits by forming organized, multilayered structures.The formation of biofilms occurs through four key stages: attachment, colonization, development, and dispersal.During attachment, free-swimming planktonic cells adhere to a surface, often facilitated by...
Bacterial Signaling01:30

Bacterial Signaling

Bacterial signaling can occur within bacteria (intracellular) or between bacteria (intercellular). At times, a group of bacteria behaves like a community. To achieve this, they engage in quorum sensing, the perception of higher cell density that causes changes in gene expression. Quorum sensing involves both extracellular and intracellular signaling. The signaling cascade starts with a molecule called an autoinducer (AI). Individual bacteria produce AIs that move out of the bacterial cell...

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Breast Implants: Biomaterials, Surfaces, Biocompatibility-A Biomedical Engineering Perspective.

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Functionalization of the Surface of Ti6Al4V Alloy Samples Printed Using Additive Technology DMLS for Orthopedic Applications Using Glow Discharge Treatment.

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Updated: Jul 16, 2026

Oral Biofilm Formation on Different Materials for Dental Implants
11:19

Oral Biofilm Formation on Different Materials for Dental Implants

Published on: June 24, 2018

Bacterial Biofilm and Titanium Implants: Mechanisms, Clinical Problems, and Surface Modification Strategies.

Julia Lisoń-Kubica1

  • 1Department of Biomaterials and Medical Devices Engineering, Faculty of Biomedical Engineering, Silesian University of Technology, Roosevelta 40 Street, 41-800 Zabrze, Poland.

Materials (Basel, Switzerland)
|July 15, 2026
PubMed
Summary

Bacterial biofilms on titanium implants cause chronic infections and antibiotic resistance. Surface modifications, like atomic layer deposition (ALD) with tin dioxide (SnO2), show promise for creating antibacterial coatings to prevent these issues.

Keywords:
biofilmbiomaterialssurface engineeringtitanium alloy

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Effects of Mechanical Methods Used in Peri-implantitis Treatment on Implant Surface Decontamination and Roughness
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Effects of Mechanical Methods Used in Peri-implantitis Treatment on Implant Surface Decontamination and Roughness

Published on: March 14, 2025

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Last Updated: Jul 16, 2026

Oral Biofilm Formation on Different Materials for Dental Implants
11:19

Oral Biofilm Formation on Different Materials for Dental Implants

Published on: June 24, 2018

Effects of Mechanical Methods Used in Peri-implantitis Treatment on Implant Surface Decontamination and Roughness
06:36

Effects of Mechanical Methods Used in Peri-implantitis Treatment on Implant Surface Decontamination and Roughness

Published on: March 14, 2025

Area of Science:

  • Biomaterials Science
  • Infectious Diseases
  • Surface Chemistry

Background:

  • Bacterial biofilms are a major cause of chronic implant-related infections, leading to treatment failure and increased morbidity.
  • Titanium implants, commonly used in orthopedics and dentistry, are susceptible to biofilm formation, complicating patient outcomes.
  • Antimicrobial resistance is exacerbated by persistent biofilm infections, posing significant healthcare and economic challenges.

Purpose of the Study:

  • To review the mechanisms of biofilm formation on implant surfaces.
  • To discuss the clinical implications of implant-related bacterial infections.
  • To highlight advanced surface modification strategies for combating biofilms on titanium biomaterials.

Main Methods:

  • Literature review focusing on bacterial adhesion, biofilm formation, and implant infections.
  • Analysis of titanium alloys (e.g., Ti-6Al-4V, Ti-13Nb-13Zr) regarding biocompatibility and biofilm susceptibility.
  • Evaluation of various anti-biofilm strategies, with emphasis on surface modification techniques like atomic layer deposition (ALD).

Main Results:

  • Biofilm formation on titanium implants leads to antimicrobial tolerance and difficult-to-eradicate infections.
  • Next-generation titanium alloys present specific advantages and limitations concerning biofilm formation.
  • Atomic layer deposition (ALD) offers a promising method for creating uniform, antibacterial coatings, such as tin dioxide (SnO2).

Conclusions:

  • Surface modification of titanium implants is crucial for preventing biofilm-related complications.
  • ALD technology enables the development of advanced antibacterial coatings to reduce bacterial adhesion.
  • Enhanced implant coatings can improve osseointegration and long-term implant performance, combating antimicrobial resistance.