Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Video

Updated: Jul 16, 2026

Dissolving Microneedle Array Patches Manufactured By Solvent Casting Technique and Essential Characterization of Microneedle-Based Biomedical Devices

Dissolving Microneedle Array Patches Manufactured By Solvent Casting Technique and Essential Characterization of Microneedle-Based Biomedical Devices

Published on: January 30, 2026

Shrinky Dinks-Based Bionic Meta-Microneedles for Advancing Wound Healing.

Tong Wu¹, Peizhi Yuan¹, Yuchen Pan¹

¹Jiangsu Provincial University Key Laboratory of Green Biomanufacturing for Pharmaceuticals, School of Pharmaceutical Sciences, Nanjing Tech University, Nanjing 211816, China.

ACS Applied Materials & Interfaces

|July 15, 2026

Summary

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Roles of cGAS in pulmonary pathophysiology: a multifaceted regulator and an emerging therapeutic target.

Biochemical pharmacology·2026

Same author

A sub-10-millisecond neural dynamical system based on phase-change memristors.

Science (New York, N.Y.)·2026

Same author

AI-Derived Smart Microneedle Systems for Advanced Wound Management: From Intelligent Sensing to Closed-Loop Therapy.

Macromolecular bioscience·2026

Same author

Strain-localized luminescent e-skin for high-resolution pressure mapping and visual force feedback.

Nature communications·2026

Same author

Ordered micro-nano structures: synergistic integration of microneedles and photonic crystals for advanced biomedical systems.

Journal of materials chemistry. B·2026

Same author

Computational-Aided Mutagenesis of Lipase CRL1 with Promoted Stability and Activity for Biosynthesis of Vitamin E Succinate.

Journal of agricultural and food chemistry·2026

Researchers developed novel bionic multi-structural microneedle (MN) patches inspired by nature. These pattern-tunable MN dressings offer enhanced adhesion and rapid microfluidic transport for improved wound healing applications.

Area of Science:

Biomaterials Science
Regenerative Medicine
Nanotechnology

Background:

Wound healing is a critical healthcare challenge.
Microneedle (MN) dressings are an emerging strategy for wound treatment.
Existing MN technologies face limitations in adhesion and controlled delivery.

Purpose of the Study:

To develop a novel, cost-effective method for fabricating pattern-tunable bionic multi-structural microneedle patches (PBMMs).
To enhance MN dressing adhesion and microfluidic transport for systematic wound management.
To explore biomimetic designs inspired by natural structures for improved wound healing devices.

Main Methods:

Utilized shrinky dinks to generate negative templates for microstructures.
Employed biomimetic designs inspired by frog foot pads and octopus suction cups.

Keywords:

bionic drug release microneedle motion detection structural design wound healing

More Related Videos

Fabrication of a Master Mold for Microneedles with a Micron-sized Air-vent Hole

Fabrication of a Master Mold for Microneedles with a Micron-sized Air-vent Hole

Published on: December 5, 2025

Related Experiment Videos

Last Updated: Jul 16, 2026

Dissolving Microneedle Array Patches Manufactured By Solvent Casting Technique and Essential Characterization of Microneedle-Based Biomedical Devices

Dissolving Microneedle Array Patches Manufactured By Solvent Casting Technique and Essential Characterization of Microneedle-Based Biomedical Devices

Published on: January 30, 2026

Fabrication of a Master Mold for Microneedles with a Micron-sized Air-vent Hole

Fabrication of a Master Mold for Microneedles with a Micron-sized Air-vent Hole

Published on: December 5, 2025

Fabricated pattern-tunable bionic multi-structural microneedle patches (PBMMs) with integrated hexagonal frames and annular suction cups.

Main Results:

Achieved rapid manufacturing speed and cost-effectiveness through the novel template method.
Demonstrated strong and reliable adhesion of PBMMs to wound surfaces via biomimetic structures.
Confirmed rapid, directional microfluidic transport through the unique microchannels of the PBMMs.

Conclusions:

The proposed fabrication method is versatile for various MN structure designs.
PBMMs show significant potential for next-generation clinical wound healing applications.
Biomimetic design principles can enhance the performance of microneedle-based wound care solutions.