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Mayo Test Drive Español: A model of digital cognitive test adaptation
Aimee J Karstens1,2, Paula A Aduen3, Natalia Luna Andrade1
1Department of Psychiatry and Psychology, Mayo Clinic, Rochester, MN, USA.
The Clinical Neuropsychologist
|July 15, 2026
Summary
Adapting digital cognitive tests for diverse Spanish speakers requires a mixed-methods approach. The Mayo Test Drive-Español project involved iterative feedback to refine test stimuli and instructions for better cross-cultural adaptation.
Area of Science:
- Neuroscience
- Psychology
- Linguistics
Background:
- Traditional Spanish adaptations of cognitive tests often lack cross-cultural validation.
- Existing methods prioritize fidelity over cultural relevance, potentially impacting test accuracy.
Purpose of the Study:
- To describe the adaptation of digital cognitive tests for diverse Spanish-speaking populations using a mixed-methods approach.
- To detail the iterative process of refining test stimuli and instructions through stakeholder feedback.
Main Methods:
- Recruitment of Spanish speakers for the Mayo Test Drive-Español registry.
- Qualitative analysis of virtual focus groups, including cognitive interviewing and direct feedback.
- Iterative revisions of test stimuli and instructions based on consensus and quality control.
Main Results:
- 85 participants contributed to the registry, with 38 participating in 10 focus groups.
- 8 iterative revisions of test stimuli and 9 of instructions were implemented.
- Qualitative analysis identified key themes regarding platform, construct, instructions, and content.
Conclusions:
- Early stakeholder input is crucial for effective cross-cultural adaptation of cognitive measures.
- The Mayo Test Drive-Español methodology enhances the relevance and usability of cognitive tests for diverse linguistic groups.

