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Updated: Jul 17, 2026

Ex Vivo Optogenetic Dissection of Fear Circuits in Brain Slices
Published on: April 5, 2016
Amygdala astrocytes encode anxiety states
1Center for Neuroimmunology and Glial Biology, The Brown Foundation Institute of Molecular Medicine for the Prevention of Human Diseases, University of Texas Health Science Center at Houston, Houston, TX, USA.
Abstract:
In this issue of Neuron, Ghenissa and colleagues1 show that intracellular Ca2+ signaling within populations of astrocytes in the basolateral amygdala of mice encodes anxiety states that are regulated by noradrenergic signaling through α1 adrenergic receptors. These findings identify amygdala astrocytes as a cellular element contributing to anxiety circuits.
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