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Test-fairness deep learning with influence score
Jacky Chung-Hao Wu1,2,3, Chang-Yu Shih3,4, Nien-Chen Wu3,5
1Center for Fundamental Science, Kaohsiung Medical University, Kaohsiung, Taiwan.
PLOS Digital Health
|July 16, 2026
Summary
This study introduces a novel feature selection method using the influence score (I-score) to enhance fairness in artificial intelligence (AI) models. The approach reduces performance disparities across different datasets while maintaining prediction accuracy.
Area of Science:
- Artificial Intelligence
- Machine Learning
- Computer Science
Background:
- AI performance disparities can arise from training data collected from specific populations, leading to unequal outcomes across sensitive groups or data sources.
- Ensuring fairness and equitable performance in AI models across diverse datasets is a critical challenge in machine learning.
Purpose of the Study:
- To propose and evaluate a feature-selection-based method for improving test-fairness in deep learning models.
- To reduce cross-dataset subgroup performance disparity while preserving overall prediction performance.
Main Methods:
- Developed a feature-selection approach leveraging the influence score (I-score) to identify and mask dataset-associated features.
- Trained an auxiliary model to predict dataset origin and used I-score to select features strongly linked to dataset membership.
- Applied the method to deep learning models for skin lesion classification using two distinct datasets (ISIC 2019 and ASAN).
Main Results:
- The proposed fair I-score model successfully reduced cross-dataset subgroup performance disparity.
- High classification performance for skin lesion prediction was maintained after applying the fairness intervention.
- Empirical results demonstrated the effectiveness of the method on real-world skin lesion datasets from different populations.
Conclusions:
- Feature selection using the influence score is an effective strategy for enhancing test-fairness in AI models.
- The proposed method offers a practical solution for mitigating performance disparities in AI systems trained on heterogeneous data.
- This approach contributes to the development of more equitable and reliable AI applications, particularly in medical image analysis.
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