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A Direct, Regioselective and Atom-Economical Synthesis of 3-Aroyl-N-hydroxy-5-nitroindoles by Cycloaddition of 4-Nitronitrosobenzene with Alkynones
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Toward a Click-to-Click Strategy Enabled by Sequential Reverse Cope Cyclization and Strain-Promoted Alkyne-Nitrone

Vivien Herrscher1, Agathe Martinez1,2, Alexis Vallée1,2

  • 1Université de Reims Champagne-Ardenne, CNRS, ICMR, Reims51687, France.

Organic Letters
|July 17, 2026
PubMed

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