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Borderline Myxoid Adrenocortical Neoplasm: A Case Report
Maria-Anthi Chantzi1, Theodoros Sidiropoulos2, Spyridon Christodoulou2
1School of Medicine, National and Kapodistrian University of Athens, Athens, GRC.
Cureus
|July 17, 2026
Summary
This case report details a rare borderline malignant myxoid adrenocortical neoplasm (BMAN). Early diagnosis and surgical excision led to a favorable outcome, highlighting diagnostic challenges and the need for further research.
Area of Science:
- Endocrinology
- Oncology
- Pathology
Background:
- Myxoid adrenocortical neoplasm (MAN) is an exceptionally rare adrenal tumor variant.
- A subset of MANs possess borderline malignant potential (BMAN), posing diagnostic challenges due to predominant myxoid stroma obscuring malignancy assessment.
- Extensive myxoid stroma can hinder the application of traditional criteria like the Weiss score for risk stratification.