Related Experiment Video

Updated: Aug 6, 2026

Mouse Naïve CD4+ T Cell Isolation and In vitro Differentiation into T Cell Subsets
07:12

Mouse Naïve CD4+ T Cell Isolation and In vitro Differentiation into T Cell Subsets

Published on: April 16, 2015

Sensory neurons shape γδ T cell effector programs to control Psoriasiform Inflammation

Juan M Inclan-Rico1,2,3, Camila M Napuri1,4,3, Adriana Stephenson1,4

  • 1Department of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.

Biorxiv : the Preprint Server for Biology
|July 17, 2026
PubMed
Summary

Sensory neuron subsets, specifically non-peptidergic NP1 and NP2, differentially modulate psoriasis. NP1 activation suppresses inflammation, while NP2 activation exacerbates it by altering T cell profiles.

Keywords:
NeuroimmunologyPsoriasisSkingamma delta T cells

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