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A Review of Chronic Comorbidities in People Living With HIV in Peru
Marleny Nolasco1, Evelyn Hsieh2, Patricia J Garcia3
1Department of Neurology, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, NC, USA.
Abstract:
BackgroundAdvances in antiretroviral therapy (ART) have extended the life expectancy of people living with HIV (PWH) in Peru, shifting the healthcare focus toward managing chronic non-communicable comorbidities (NCDs). Yet data on NCD burden among aging PWH in Peru are sparse.MethodsWe conducted a scoping review of peer-reviewed studies from PubMed and LILACS, in English or Spanish, that assessed non-AIDS comorbidities in Peruvian adults with HIV.ResultsWe identified 23 studies, all from Lima, mostly cross-sectional or retrospective, involving predominantly male ART patients. Commonly investigated comorbidities included neurocognitive impairment, mental health disorders (especially depression), cardiovascular disease, and metabolic syndrome; bone disease and non-AIDS malignancies were less studied.ConclusionsFindings suggest frequent cognitive, metabolic, and cardiovascular issues among PWH. Yet critical gaps remain: little is known about frailty, disability, or long-term outcomes. Expanded screening, longitudinal studies, and integrated care models are needed to improve long-term health in aging PWH in Peru.
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