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Higher order aberrations and visual quality after refractive surgeries for myopia: a systematic review and network
Tingting Chen1, Furong Li2, Dong Fang2
1The First Hospital of Lanzhou University (The First Clinical Medical College of Lanzhou University), No. 1 Donggang West Road, Chengguan District, Lanzhou, 730000, Gansu, China.
Implantable Collamer Lens (ICL) surgery is superior for reducing higher-order aberrations (HOAs) and improving visual quality compared to other refractive surgeries. ICL offers optimal optical quality, especially for high myopia.
Area of Science:
- Ophthalmology
- Refractive Surgery
- Optical Science
Background:
- Higher-order aberrations (HOAs) impact visual quality after refractive surgery.
- Comparing the efficacy of various refractive surgery techniques on HOAs is crucial for patient selection and outcomes.
Purpose of the Study:
- To compare the impact of eight refractive surgery techniques on HOAs and visual quality in adults with myopia.
- To identify the most effective refractive surgery for minimizing HOAs and enhancing visual performance.
Main Methods:
- Bayesian network meta-analysis of 50 studies involving 5,141 eyes.
- Systematic literature search across major databases (PubMed, Embase, Web of Science, Cochrane Library, ClinicalTrials.gov).
- Primary outcomes included total HOAs, spherical aberration, and coma; risk of bias assessed using Cochrane and Newcastle-Ottawa tools.
Main Results:
- Implantable Collamer Lens (ICL) demonstrated superiority in reducing total HOAs compared to SMILE, FS-LASIK, LASIK, PRK, LASEK, FLEx, and T-PRK.
- ICL significantly reduced spherical aberration and coma more effectively than other interventions (P < 0.05).
- Surface Under the Cumulative Ranking (SUCRA) analysis consistently ranked ICL as the most effective for minimizing HOAs, spherical aberration, and coma.
Conclusions:
- ICL implantation shows superior clinical outcomes in reducing total HOAs, spherical aberration, and coma.
- ICL is a recommended option for refractive correction, particularly for patients with high myopia or large pupils requiring optimal optical quality.
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