Related Experiment Videos

The pharmacist's role in the periprocedural management of anticoagulation in Canada: A qualitative study protocol

Chioma S Okpalaora1, Stephanie W Young1,2, Tiffany A Lee1,2

  • 1School of Pharmacy, Memorial University, St. John's, Newfoundland and Labrador, Canada.

Plos One
|July 17, 2026
PubMed

Insights

Canadian pharmacists play a key role in periprocedural anticoagulation management (PAM) for patients on anticoagulants. This study explores their experiences, roles, and practice variations across Canada.

Area of Science:

  • Pharmacology and Pharmaceutical Sciences
  • Health Services Research
  • Qualitative Health Research

Background:

  • Anticoagulants are vital for managing thromboembolic disorders but require careful risk balancing during procedures.
  • Coordinated periprocedural anticoagulation management (PAM) is essential to mitigate bleeding and clotting risks.
  • Canadian pharmacists possess the expertise for PAM, yet their specific roles and practice contexts are under-researched.

Purpose of the Study:

  • To explore the roles and experiences of Canadian pharmacists in periprocedural anticoagulation management (PAM).
  • To understand the variations in PAM practice based on pharmacist demographics and practice characteristics.
  • To identify barriers, facilitators, and organizational structures influencing pharmacists' PAM practice across Canada.

Main Methods:

  • A qualitative description study employing constructionism and naturalism.
  • Semi-structured virtual interviews with licensed Canadian pharmacists experienced in PAM.
  • Conventional qualitative content analysis of transcribed interviews to identify themes and categories.

Main Results:

  • The study will provide an in-depth understanding of pharmacists' current roles in PAM across Canada.
  • It will detail the contextual factors influencing PAM practice in diverse Canadian settings.
  • Variations in practice related to demographic and professional characteristics will be explored.

Conclusions:

  • Findings will address critical gaps in the literature regarding pharmacists' contributions to PAM in Canada.
  • Results can inform the development of future PAM service models and professional training programs.
  • The research aims to support improved care coordination and patient outcomes in Canadian anticoagulation services.

Related Concept Videos

Venous Thrombosis III: Interprofessional Care01:29

Venous Thrombosis III: Interprofessional Care

Venous thrombosis requires effective prevention and treatment strategies to improve patient outcomes and reduce potential complications.Prevention StrategiesHealthcare providers must prioritize preventing venous thromboembolism (VTE) for all adult patients upon admission. Interventions depend on bleeding and thrombosis risk, medical history, current medications, diagnoses, planned procedures, and patient preferences. Patients on bed rest should change positions every two hours and, if not...
Anticoagulant Drugs: Low-Molecular-Weight Heparins01:30

Anticoagulant Drugs: Low-Molecular-Weight Heparins

Hemostasis is a crucial process that prevents excessive blood loss from damaged blood vessels. It involves various mechanisms such as vasoconstriction, platelet adhesion and activation, and fibrin formation. The importance of each mechanism depends on the type of vessel injury. In contrast, thrombosis is the abnormal formation of a blood clot within the blood vessels, leading to potential complications if the clot obstructs blood flow. Thrombosis can be caused by increased coagulability of the...
Coronary Artery Disease V: Interprofessional Care01:27

Coronary Artery Disease V: Interprofessional Care

Interprofessional care for coronary artery disease includes pharmacological therapy and revascularization procedures.Pharmacological therapy for Coronary Artery Disease (CAD) aims to manage symptoms, prevent complications, and improve patient outcomes through various classes of medications:Antiplatelet Agents:Aspirin and Clopidogrel: These medications inhibit platelet aggregation, preventing blood clots, which is crucial for avoiding heart attacks and strokes. Doctors often prescribe these...
Anticoagulant Drugs: Vitamin K Antagonists and Direct Oral Anticoagulants01:18

Anticoagulant Drugs: Vitamin K Antagonists and Direct Oral Anticoagulants

Oral anticoagulants are vital tools in preventing and treating blood clotting disorders. This diverse class of medications can be categorized as vitamin K antagonists, exemplified by warfarin, and direct thrombin inhibitors (DTIs), such as dabigatran, as well as factor Xa inhibitors, including rivaroxaban.
Warfarin, a prominent vitamin K antagonist family member, exerts its effect by inhibiting the enzyme VKORC1 (vitamin K epoxide reductase complex 1). By hindering this enzyme, warfarin...
Cardiac Catheterization IV: Nursing Management01:26

Cardiac Catheterization IV: Nursing Management

Nursing responsibilities before cardiac catheterization include:Assess for allergies and establish baseline health status.Before cardiac catheterization, assess the patient for allergies to contrast dye. Perform a comprehensive baseline assessment, including vital signs, heart and breath sounds, and a neurovascular assessment of the extremities, noting distal pulses, skin color, and temperature. Instruct the patient to fast for 8-12 hours before the procedure. Evaluate baseline laboratory...
Acute Coronary Syndrome IV: Interprofessional Care01:28

Acute Coronary Syndrome IV: Interprofessional Care

IntroductionThe management of Acute Coronary Syndrome (ACS) aims to minimize myocardial damage, preserve myocardial function, and prevent complications.Initial ManagementInpatient management involves continuous cardiac monitoring, preferably in an ICU, focusing on blood pressure, serum sodium, potassium, and creatinine levels, and urine output. Ongoing pharmacologic management is crucial for stabilizing the patient.Supplemental Oxygen: Administer supplemental oxygen if oxygen saturation is...