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Multitask learning-based phonocardiogram denoising model for preserving valvular heart disease characteristics
Geon Lee1, Hangsik Shin1,2
1Department of Medical Informatics and Statistics, Brain Korea 21 Project, Asan Medical Center, University of Ulsan College of Medicine, Seoul 05505, Republic of Korea.
Abstract:
Objective.This study developed a multitask learning (MTL)-based denoising model to reconstruct phonocardiogram (PCG) signals while preserving heart murmur characteristics under both synthetic and diverse real-world clinical noise.Approach.The model was trained to jointly denoise PCG data and classify valvular heart disease (VHD). The original PCG dataset comprised recordings lasting up to 3 s, including normal heart sounds and four VHD classes, with 200 samples per class. To construct inputs, we synthesized contaminated PCGs by mixing synthetic and real-world clinical noise sources and converted them into spectrogram images. The model was evaluated at signal-to-noise ratios (SNRs) of -5, 0, 5, and 10 dB using 5 × 5 nested cross-validation. Denoising performance was measured by the scale-invariant signal-to-distortion ratio (SI-SDR), and VHD classification by accuracy.Main results.Our model outperformed a single-task U-Net denoising baseline; even at a highly contaminated SNR of -5 dB, it achieved an absolute mean SI-SDR of 14.05 dB. For real-world noise, including hospital ambient noise and lung sounds, our model improved SI-SDR by up to 9.69 dB over previous work. For VHD classification, the model exceeded 98.5% accuracy across most conditions at SNRs of 5 and 10 dB, suggesting that heart murmur-specific features were preserved during denoising.Significance.Overall, this MTL-based model demonstrated consistent and robust PCG reconstruction across diverse noise conditions, improving VHD classification on contaminated PCG signals.
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