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Functional Status and Health-Related Quality of Life Among Survivors of Cardiogenic Shock

Eric J Hall1, Sachin Agarwal2, Colby R Ayers3

  • 1Division of Cardiology, Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas, USA; Parkland Health and Hospital System, Dallas, Texas, USA.

JACC. Heart Failure
|July 18, 2026
PubMed

Insights

Cardiogenic shock (CS) survivors face significant functional disability and lower quality of life post-discharge. Pain and mobility issues are common, highlighting the need for improved recovery strategies.

Area of Science:

  • Cardiology
  • Patient-centered outcomes research
  • Quality of life studies

Background:

  • Limited data exist on patient-centered outcomes for cardiogenic shock (CS) survivors post-discharge.
  • Functional status and health-related quality of life (HRQoL) are critical but understudied aspects of CS recovery.

Purpose of the Study:

  • To evaluate patient-centered outcomes, including functional status and HRQoL, in survivors of cardiogenic shock (CS).

Main Methods:

  • Prospective cohort study of CS survivors (Society of Coronary Angiography and Intervention Stage C or greater).
  • Primary outcome: functional disability at 3 months (modified Rankin Scale ≥2).
  • Secondary outcome: HRQoL assessed via EQ-5D at 3 months.

Main Results:

  • 118 CS survivors completed 3-month follow-up; 46% experienced functional disability.
  • Common issues included pain (67%), mobility limitations (48%), and anxiety/depression (35%).
  • Median EQ-5D Index Score (0.84) was below US population norms; functional status correlated inversely with HRQoL (r = -0.68).

Conclusions:

  • CS survivors exhibit substantial functional limitations and diminished HRQoL up to 3 months post-discharge.
  • Pain and mobility impairments are prevalent, impacting overall recovery.
  • Further research is needed to optimize multidomain recovery strategies for CS survivors.
Abstract

Keywords:
cardiogenic shockfunctional statusmechanical circulatory supportquality of lifesurvivorship

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