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Updated: Aug 6, 2026

A Novel Technique for Generating and Observing Chemiluminescence in a Biological Setting
08:57

A Novel Technique for Generating and Observing Chemiluminescence in a Biological Setting

Published on: March 9, 2017

Oxygen-Driven [2 + 2] Photocycloaddition for In Vivo Chemiluminescence

Yutao Zhang1, Juan Li1, Ruihua Pu2

  • 1Key Laboratory for Advanced Materials and Joint International Research Laboratory of Precision Chemistry and Molecular Engineering, Feringa Nobel Prize Scientist Joint Research Center, Institute of Fine Chemicals, Frontiers Science Center for Materiobiology and Dynamic Chemistry, School of Chemistry and Molecular Engineering, State Key Laboratory of Bioreactor Engineering, State Key Laboratory of Green Chemical Engineering and Industrial Catalysis, Center of Photosensitive Chemicals Engineering, East China University of Science and Technology, Shanghai 200237, China.

Journal of the American Chemical Society
|July 20, 2026
PubMed
Summary

Researchers developed a new method for in vivo chemiluminescence using oxygen and special molecules called Rubines. This breakthrough enables brighter, real-time imaging for diagnostics and monitoring biological processes like blood-brain barrier repair.

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