Customized Intraoral Appliances for Self-Inflicted Oral Injuries in Pediatric Neurological Disorders: A Case Series

Self-inflicted oral injuries in children with neurological disorders represent a significant clinical concern due to their multifactorial impact on oral and systemic health. Neurological disorders, such as febrile infection-related epilepsy syndrome (FIRES) and glutaric aciduria type I, may cause dystonia, involuntary orofacial movements, and self-inflicted biting, resulting in oral trauma. Management typically requires an interdisciplinary approach combining behavioral and pharmacologic strategies with protective intraoral appliances and, in selected cases, to prevent further trauma and preserve function. Three pediatric cases with neurological disorders in this series presenting with self-inflicted oral injuries were successfully managed with a customized intraoral appliance. All children showed mucosal healing within 7-10 days and no recurrence of trauma during the periodic follow-ups. Customized appliances provided effective protection, durability, and hygiene compatibility.