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Cefoperazone-treated Mouse Model of Clinically-relevant Clostridium difficile Strain R20291
Published on: December 10, 2016
Complete genome sequence of Clostridioides difficile NCTC 12727, a PCR ribotype 001 reference strain
Samiksha Venkatesan1, Michael Macey2, Uzaira Saniah1
1Anaerobes in Medicine (AiM Lab), School of Life, Health and Chemical Sciences, The Open University, Milton Keynes, United Kingdom.
Microbiology Resource Announcements
|July 20, 2026
Abstract
None:
We report the complete genome sequence of the PCR ribotype 001 Clostridioides difficile strain NCTC 12727 obtained by hybrid genome assembly, manual curation, and PCR validation. The circular 4,371,963 bp genome (28.99% GC) contained two multi-copy mobile genetic elements encompassing a prophage and a Tn916-like element, respectively.

