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Updated: Aug 9, 2026
Inverse Probability of Treatment Weighting (Propensity Score) using the Military Health System Data Repository and National Death Index
Published on: January 8, 2020
Long-term outcomes after bentall-de bono versus modified bentall-de bono procedures: a propensity score-matched
Song Wang1, Meng He1, Jinwei Zhang1
1Department of Cardiovascular Surgery Center, Beijing Institute of Heart, Lung and Blood Vascular Diseases, Capital Medical University Affiliated Beijing Anzhen Hospital, No. 225, Songzhuang South 1st Street, Tongzhou District, Beijing, 101118, China.
Objective:
To evaluate the impact of Bentall-de Bono (BD) versus modified Bentall-de Bono (MBD) procedures on patient survival and long-term clinical outcomes.
Methods:
We reviewed 1,478 patients who underwent Bentall procedures between 2003 and 2022. Patients were initially stratified into two groups based on surgical technique: the BD group (n = 1,274), and the MBD group (n = 204). To mitigate baseline imbalances and selection bias, a 1:1 propensity score matching analysis was performed, yielding 202 matched pairs. Long-term survival was assessed using Kaplan-Meier analysis. Stroke was analyzed as an exploratory secondary cerebrovascular outcome. Predictors of mortality were identified via multivariable Cox proportional hazards regression.
Results:
In the matched cohort, the median follow-up was 5.98 (interquartile range: 3.53-9.84) years. Kaplan-Meier analysis demonstrated comparable 10-year survival rates between the BD and MBD groups (90.9% vs. 88.4%, P = 0.42). Freedom from stroke was evaluated exploratorily and did not differ significantly between groups. (80.0% vs. 80.2%, P = 0.63). Multivariable Cox regression confirmed that the surgical technique (BD vs. MBD) was not an independent predictor of long-term mortality (hazard ratio [HR], 0.84; 95% confidence interval [CI], 0.40-1.74; P = 0.634). Independent predictors of late mortality included advanced age and prolonged aortic cross-clamp time.
Conclusion:
There is no difference in long-term survival following BD versus MBD.