Induced Molecular Orientation Transition via Organic-Inorganic Hybrid Networks in Thin-Film Transistor-Based...

Molecular orientation transition is a key determinant of charge transport efficiency in thin-film transistors (TFTs). Conventional strategies to induce such transitions often result in increased molecular disorder, which leads to device performance degradation. Herein, an organic-inorganic hybrid network was proposed to modulate the structure-performance relationship via the incorporation of specific inorganic metal oxides (e.g., In₂O₃), leading to a marked enhancement in device and sensing performance by nearly 20-fold. This phenomenon may be associated with a triple-condition mechanistic framework involving strong interfacial adsorption, thermodynamic driving force, and abundant oxygen vacancies. The proposed triple-condition mechanistic framework not only transforms molecular orientation from observation into a predictable rule for selecting inorganic additives in organic-inorganic hybrid networks, but also establishes a practical route for improving biosensing performance through molecular orientation in life and health monitoring.