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Association Between Delayed Metabolic and Bariatric Surgery Completion and Postoperative Cardiometabolic Outcomes
Sophia Ngenge1, Folefac Atem2, Jackson M Francis1
1Department of Epidemiology, O'Donnell School of Public Health, The University of Texas Southwestern Medical Center, Dallas, TX, USA.
Obesity Surgery
|July 21, 2026
Summary
Delays in metabolic and bariatric surgery (MBS) are linked to poorer cardiometabolic health post-operation. Prompt MBS completion is associated with better cholesterol and HbA1c levels, highlighting the need for timely surgical access.
Area of Science:
- Cardiology
- Endocrinology
- Metabolic Surgery
Background:
- Delays in metabolic and bariatric surgery (MBS) are common.
- These delays may negatively impact postoperative cardiometabolic recovery.
Purpose of the Study:
- To investigate the association between delayed MBS completion and cardiometabolic outcomes over 24 months.
- To evaluate differences in postoperative cardiometabolic biomarkers based on MBS timing.
Main Methods:
- Prospective longitudinal cohort study of 172 adults undergoing MBS.
- Measurement of weight and cardiometabolic biomarkers (lipids, HbA1c) pre-MBS and at 6, 12, and 24 months post-MBS.
- Generalized estimating equations used to analyze associations between MBS timing (early vs. delayed) and outcomes, adjusting for covariates.
Main Results:
- Delayed MBS completion (>3 months post-referral) was associated with higher total cholesterol, non-HDL cholesterol, cholesterol/HDL ratio, and HbA1c levels compared to early completion (≤3 months).
- Significant improvements in triglycerides, HDL, non-HDL cholesterol, cholesterol/HDL ratio, weight, glucose, and HbA1c were observed over 24 months post-MBS.
- Women showed higher levels of total cholesterol, HDL, LDL, and non-HDL cholesterol compared to men.
Conclusions:
- Delayed MBS completion is linked to less favorable postoperative cardiometabolic profiles.
- Findings underscore the importance of reducing delays in MBS access for optimal patient outcomes.
- Timely surgical care is crucial for improving cardiometabolic health following MBS.
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