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Updated: Aug 6, 2026

A High-Throughput Multiplexed Screening for Type 1 Diabetes, Celiac Diseases, and COVID-19
Published on: July 5, 2022
Recent Advances in the Management of Type 1 Diabetes in Children
1Department of Pediatrics, Texas Tech University Health Sciences Center, 3601 4th Street, Stop 9406, Lubbock, TX 79430, USA.
Abstract:
Type 1 diabetes is an autoimmune-mediated disease affecting persons with a genetic predisposition. Screening for the presence of pancreatic autoantibodies has enabled identification of persons who can benefit from immunomodulatory therapies, with one anti-CD3 monoclonal antibody therapy now in clinical use. Other therapies under investigation include those related to β-cell replacement and regeneration. Diabetes device technology has progressed rapidly, with continuous glucose monitoring and automated insulin delivery via closed-loop systems providing for improved glycemic control and enhanced quality of life.
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