Related Experiment Video
Updated: Aug 6, 2026
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A Simplified Stepwise Approach to Echo Guidance during Percutaneous Mitral Valve Repair
Published on: October 16, 2021
Transcatheter Tricuspid Valve Annuloplasty vs Edge-to-Edge Repair: A Propensity-Matched Multicenter Comparative
Jennifer von Stein1, Philipp von Stein1, Lukas Stolz2
1Department of Cardiology, Heart Center, University of Cologne, Cologne, Germany; Cardiovascular Research Foundation, New York, New York, USA.
JACC. Advances
|July 22, 2026
Summary
Transcatheter tricuspid valve edge-to-edge repair (T-TEER) offers better safety and TR reduction than transcatheter tricuspid valve annuloplasty (TTVA). However, 1-year clinical outcomes were similar, warranting longer-term follow-up for severe secondary TR patients.
Area of Science:
- Cardiology
- Interventional Cardiology
- Cardiac Surgery
Background:
- Transcatheter tricuspid valve (TV) interventions are crucial for severe symptomatic tricuspid regurgitation (TR).
- Transcatheter tricuspid valve edge-to-edge repair (T-TEER) and transcatheter TV annuloplasty (TTVA) are distinct repair strategies.
- Comparative data between T-TEER and TTVA are limited.
Purpose of the Study:
- To compare procedural and clinical outcomes of T-TEER versus TTVA.
- To evaluate effectiveness and safety in patients with severe secondary TR.
Main Methods:
- A retrospective analysis of consecutive T-TEER or TTVA patients (2017-2024).
- 1:1 propensity-score matching was employed.
- Key endpoints included residual TR, procedural complications, symptomatic improvement, reinterventions, and 1-year mortality or heart failure hospitalization.
Main Results:
- T-TEER demonstrated higher rates of residual TR ≤1+ and ≤2+ compared to TTVA at discharge.
- Procedural complications were significantly lower with T-TEER (4.5% vs 27.0%).
- One-year freedom from all-cause mortality or heart failure hospitalization was comparable (75.0% for T-TEER vs 79.8% for TTVA).
Conclusions:
- T-TEER exhibits a more favorable safety profile and superior TR reduction compared to TTVA.
- Early clinical outcomes at 1 year were similar between T-TEER and TTVA after adjustment.
- Longer-term evaluation is necessary to fully assess the durability and impact of these interventions.
