How to optimise prostate SBRT: ESTRO clinical practice consensus recommendations

A steady rise in the number of patients receiving stereotactic body radiation therapy (SBRT) for primary prostate cancer is expected. Consequently, the current European Society for Radiotherapy and Oncology (ESTRO) 'how to' consensus has been developed to offer practical recommendations for the initiation and implementation of prostate SBRT in radiotherapy (RT) departments. A panel of fifteen experts in the field of prostate SBRT reviewed and analysed the literature and, through a Delphi process, answered a ten-item questionnaire addressing areas of controversy in prostate SBRT. Consensus was a priori defined as ≥75% agreement in each answer, while ≥90% agreement was defined as strong consensus. The aim of this 'how to' consensus recommendations is to define minimum requirements, common practices and additional options for prostate SBRT based on scientific evidence, expert opinion and consensus. This 'how to' clinical practice recommendations cover patient selection and follow-up process, treatment planning and delivery techniques in prostate SBRT.