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Status Epilepticus in Pediatric Patients Severity Score: A Clinical Score to Predict the Outcome of Status
Dama Mahesh1, Anilkumar Sajjan, V J Prakash
1Department of Pediatrics, Shri B. M. Patil Medical College Hospital and Research Centre, BLDE (DU), Vijayapura, Karnataka, India.
Insights
The Status Epilepticus in Pediatric Patients Severity Score (STEPSS) effectively predicts outcomes in children with status epilepticus (SE). A lower STEPSS score indicates survival, while higher scores are linked to mortality and poor neurological outcomes.
Area of Science:
- Pediatric critical care medicine
- Neurology
- Clinical risk assessment
Background:
- Status epilepticus (SE) in children presents significant morbidity and mortality risks.
- Early identification of high-risk pediatric SE patients is crucial for improving outcomes.
- The Status Epilepticus in Pediatric Patients Severity Score (STEPSS) is a clinical tool for predicting SE outcomes.
Purpose of the Study:
- To evaluate the clinical utility of the STEPSS score in predicting outcomes for pediatric patients with SE.
- To assess the effectiveness of STEPSS in identifying children at high risk of adverse outcomes from SE.
Main Methods:
- A cross-sectional study involving 50 children (1 month to 16 years) with SE (seizures ≥5 min).
- STEPSS was calculated upon admission based on clinical parameters.
- Patient outcomes were assessed clinically; statistical analysis used SPSS v26.
Main Results:
- 60% of children had a STEPSS score of 3 or higher.
- Mortality was observed in 26.7% of children with STEPSS ≥3, versus survival in those with STEPSS ≤2 (P=0.0117).
- Higher STEPSS scores correlated with significantly worse neurological outcomes and mortality.
Conclusions:
- The STEPSS score is a valuable tool for the early prediction of outcomes in pediatric status epilepticus.
- STEPSS demonstrates high sensitivity and a high Negative Predictive Value for identifying favorable outcomes.
- Despite lower specificity, STEPSS aids in risk stratification for pediatric SE.
Background:
Status epilepticus (SE) is a life-threatening condition in children, which is associated with significant morbidity and mortality. Early identification of high-risk patients with SE is of utmost importance to improve their outcome. The Status Epilepticus in Pediatric Patients Severity Score (STEPSS) is a simple clinical tool designed to predict the outcome of children with SE.
Objective:
The present study aimed to evaluate the clinical utility of the STEPSS score in predicting the outcome in children with SE.
Materials And Methods:
This was a cross-sectional study conducted in a pediatric intensive care unit of a tertiary care hospital for a period of 22 months. The study included 50 children aged 1 month to 16 years who presented with seizures for ≥5 min. STEPSS was calculated on admission using clinical parameters. The outcome was assessed by clinical status. Statistical analysis was done using SPSS version 26.
Results:
Of the 50 children with SE, 30 (60%) had STEPSS ≥3. Children with a lower STEPSS score (≤2) survived, whereas mortality was observed in 26.7% of those with STEPSS ≥3 (P = 0.0117). Unfavorable neurological outcomes were significantly higher in the ≥3 group. The STEPSS score demonstrated a sensitivity of 100% and specificity of 47.62% for predicting mortality with a diagnostic accuracy of 56%.
Conclusion:
The STEPSS is a useful clinical tool for early prediction of outcome in children with SE. Despite high sensitivity and low specificity, the test showed a high Negative predictive value, making it useful in identifying children with a favorable outcome.
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