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Published on: July 28, 2026
Recent progress in postoperative nausea and vomiting after thyroidectomy
Qihao Zhao1,2, Fuling Song3, Meimei Cui4
1Department of General Surgery, The First Affiliated Hospital of Shandong First Medical University & Shandong Provincial Qianfoshan Hospital, Jinan, China.
Postoperative nausea and vomiting (PONV) after thyroidectomy is common. Multimodal prophylactic strategies, including anesthesia choices and antiemetics, are key to reducing its incidence and improving patient recovery.
Area of Science:
- Anesthesiology
- Otolaryngology
- Surgical Complications
Background:
- Postoperative nausea and vomiting (PONV) is a frequent and significant complication after thyroidectomy.
- Vomiting can exacerbate surgical risks such as hematoma, bleeding, and delayed recovery.
Purpose of the Study:
- To review current knowledge on PONV following thyroidectomy.
- To emphasize thyroidectomy-specific factors and perioperative strategies for prevention and treatment.
Main Methods:
- This narrative review synthesizes information from recent literature.
- Focuses on epidemiology, mechanisms, risk factors, and evidence-based prevention and treatment strategies.
Main Results:
- PONV pathophysiology is multifactorial, influenced by surgical stimuli, anesthesia, and patient susceptibility.
- Risk factors include female sex, non-smoker status, motion sickness history, and specific anesthetic agents.
Conclusions:
- Multimodal prophylaxis, including TIVA, opioid-sparing techniques, and antiemetics (5-HT3 antagonists, corticosteroids), is recommended.
- Individualized risk assessment and tailored antiemetic strategies are crucial for optimal outcomes in thyroidectomy patients.
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