A dicyanoisophorone-based fluorescent probe for highly selective recognition of F⁻

In this study, a novel pyrazole derivative DCI-1 was rationally designed and synthesized using dicyanoisophorone as the fluorophore. The optical properties and recognition performance of DCI-1 were systematically investigated. Experimental results verified that the addition of F⁻ induced obvious fluorescence quenching of probe DCI-1, accompanied by a color change of the solution from yellow to colorless. Probe DCI-1 exhibits excellent recognition capability toward F⁻ with high selectivity and sensitivity. The limit of detection was calculated to be 1.57 × 10^-7 mol/L. Moreover, the distinct color variation endows DCI-1 with outstanding naked-eye recognition ability for F⁻.