Related Experiment Video
Updated: Aug 6, 2026

Using a Murine Model of Psychosocial Stress in Pregnancy as a Translationally Relevant Paradigm for Psychiatric Disorders in Mothers and Infants
Published on: June 13, 2021
Maternal mental health and its influence on children's early development: Evidence from Khyber Pakhtunkhwa, Pakistan
Elizabeth Hentschel1,2, Amer Hasan1, Mahreen Tahir-Chowdhry1
1Education Global Practice, World Bank, Washington, USA.
Little is known about the prevalence of maternal mental health challenges in Khyber Pakhtunkhwa, Pakistan and the ways in which it may influence the development outcomes of young children. This study describes the prevalence of three measures of maternal mental health: depression, anxiety and parenting stress, and assesses whether they independently or jointly predict early child development (ECD) even after accounting for stressors such as poverty, low access to quality education and limited social assistance. A population-proportionate, cluster-randomized household survey was conducted collecting data from a total of 1397 children aged 0-35-months-old and 705 children aged 36-72-months-old and their mothers. Unadjusted and adjusted Ordinary Least Squares linear regression analyses were run for the independent and joint association of maternal depression, anxiety, and parenting stress on ECD. There is a substantial prevalence of mental health concerns among the mothers in our sample-with several mental health concerns co-occurring. Maternal depression, anxiety, and parenting stress have a significant, negative and compounding interaction on child development for younger and older children, even after controlling for stressors and other covariates. Policy improvements are needed that focus on at-risk communities, providing mental health services and reducing exposure to stressors within communities and households.
Little is known about the prevalence of maternal mental health challenges in Khyber Pakhtunkhwa, Pakistan and the ways in which it may influence the development outcomes of young children. This study describes the prevalence of three measures of maternal mental health: depression, anxiety and parenting stress, and assesses whether they independently or jointly predict early child development (ECD) even after accounting for stressors such as poverty, low access to quality education and limited social assistance. A population-proportionate, cluster-randomized household survey was conducted collecting data from a total of 1397 children aged 0-35-months-old and 705 children aged 36-72-months-old and their mothers. Unadjusted and adjusted Ordinary Least Squares linear regression analyses were run for the independent and joint association of maternal depression, anxiety, and parenting stress on ECD. There is a substantial prevalence of mental health concerns among the mothers in our sample-with several mental health concerns co-occurring. Maternal depression, anxiety, and parenting stress have a significant, negative and compounding interaction on child development for younger and older children, even after controlling for stressors and other covariates. Policy improvements are needed that focus on at-risk communities, providing mental health services and reducing exposure to stressors within communities and households.
More Related Videos
09:09Generating a Reproducible Model of Mid-Gestational Maternal Immune Activation using Poly(I:C) to Study Susceptibility and Resilience in Offspring
Published on: August 17, 2022
05:04A Common Marmoset Model of Mother-Infant Intervention for Breastfeeding Disorders in the Presence of Paternal Inhibition and Maternal Neglect
Published on: September 22, 2023
Related Concept Videos
Socioemotional Development during Infancy
Primary Temperament Types
Stella Chess...
Psychological and Sociocultural Causes of Schizophrenia
Socioemotional Experience and Gender Development
Relationship with Parents: Attachment
Stress and Mental Health
Individuals with depression often experience challenges in both their personal and professional...
Environmental Influences on Intelligence