Local Triamcinolone Injection versus Anti-Tuberculosis Triple Therapy for Non-Puerperal Mastitis: A Comparative Study

Area of Science:

• Medical research
• Clinical study
• Surgical oncology

Background:

• Non-puerperal mastitis (NPM) presents a clinical challenge requiring effective treatment strategies.
• Comparing therapeutic outcomes is crucial for optimizing patient care in breast surgery.

Purpose of the Study:

• To compare the efficacy of local triamcinolone injection versus anti-tuberculosis triple therapy for non-puerperal mastitis (NPM).
• To evaluate treatment duration, remission rates, and adverse reactions between the two therapeutic approaches.

Main Methods:

• A retrospective cohort study involving 92 patients diagnosed with NPM.
• Patients were divided into two groups: triamcinolone injection and anti-tuberculosis triple therapy.
• Outcomes analyzed included remission rates, treatment duration, and complication rates.

Main Results:

• The triamcinolone group showed significantly shorter treatment duration (median 41.5 days vs. 120 days) and lower complication rates (13.6% vs. 66.7%) compared to the anti-tuberculosis group.
• Higher remission rates (91.95% vs. 82.35%) and partial remission rates (97.7% vs. 68.8%) were observed in the triamcinolone group.
• Multivariate analysis identified pathological type and affected area as independent factors influencing remission.

Conclusions:

• Local triamcinolone injection demonstrates superior short-term outcomes for NPM, including reduced treatment time and fewer complications.
• The findings suggest triamcinolone may be a more effective treatment option for NPM.
• Further validation through prospective randomized controlled trials is recommended.