A La_0.9Sr_0.1MnO₃ perovskite modified glassy carbon electrode for non-enzymatic electrochemical sugar detection

In this study, La_0.9Sr_0.1MnO₃ perovskite (Pe) material was successfully synthesized and subsequently integrated with chitosan (CS) and graphene oxide (GO) to form a nanocomposite, which was used to modify a glassy carbon electrode for application as a non-enzymatic electrochemical sensor for total sugar detection. The morphology and crystalline structure of the Pe material were characterized by scanning electron microscopy (SEM), X-ray diffraction (XRD), and infrared (IR) spectroscopy. The modified Pe/CS/GO/GCE electrode exhibited high sensitivity to various kinds of sugar, including glucose, sucrose, and lactose, while demonstrating excellent selectivity against common interfering substances present in canned soft drinks, such as citric acid, niacinamide, and sodium citrate. Notably, the activity of Pe/CS/GO/GCE toward glucose was studied using cyclic voltammetry (CV), showing a linear response over a concentration range from 5 to 14 mM, with a limit of detection (LOD) of 0.381 mM. The electrode was successfully applied to sugar determination in 5% intravenous glucose solution and in real food and beverage samples.