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Diclofenac Patches Promote Early Mobilization in Fragility Fractures: A Retrospective Cohort Study
Mikino Saito1, Takashi Higuchi1
1Kanazawa Red Cross Hospital, Kanazawa, Japan; Department of Orthopaedic Surgery, Graduate School of Medical Sciences, Kanazawa University, Kanazawa, Japan.
Summary
Transdermal diclofenac patches (DPs) significantly accelerated mobilization and improved walking ability in elderly patients with fragility fractures. This well-tolerated analgesic option aids functional recovery in this vulnerable population.
Area of Science:
- Geriatric Medicine
- Pain Management
- Orthopedics
Background:
- Effective pain management is vital for elderly patients with fragility fractures.
- Early mobilization and functional recovery are key goals in treating these patients.
Purpose of the Study:
- To evaluate the efficacy of transdermal diclofenac patches (DPs) for pain control.
- To assess the impact of DPs on functional recovery in elderly patients with fragility fractures.
- To test the hypothesis that DPs shorten mobilization time.
Main Methods:
- Retrospective cohort study with historical controls.
- Included patients aged ≥70 years with proximal femoral or vertebral fractures.
- Compared 30 patients treated with DPs to 30 patients not treated with DPs.
Main Results:
- DP group showed significantly shorter times to walking practice and toilet use.
- Fewer patients in the DP group experienced a decline in walking ability (vertebral fracture subgroup).
- No drug-related adverse events were reported.
Conclusions:
- DP use is linked to earlier mobilization and better preservation of walking ability.
- DPs appear to be a well-tolerated analgesic option for improving functional outcomes.
- Findings require cautious interpretation due to study design limitations.
