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Experimental Study on the Process and Performance of Laser Repair of Esophageal Tissue Adding ICG and CNT
Jun Huang1, Xijing Yan1, Hui Jiang1
1School of Material Science and Technology, Nanjing University of Science and Technology, Nanjing, China.
Abstract:
Laser tissue repair offers advantages such as concentrated energy delivery and minimal postoperative complications. The application of predressing can increase tissue strength and reduce thermal damage. This study investigates the effects of different concentrations of ICG and CNT, as well as their ratios, on the appearance, burst pressure strength, and thermal denaturation degree of esophageal tissue; carboxymethyl chitosan is introduced as the predressing matrix, and the thermal damage to esophageal tissue is evaluated based on microscopic parameters. Results indicate that at the laser power of 8 W, with ICG and CNT concentrations both at 0.01 wt.%, the burst pressure strength of tissue is 38.7 ± 1.2 mmHg and thermal damage is 6.08 × 10-5; when carboxymethyl chitosan is added, at the laser power of 7 W, the ICG concentration of 0.01 wt.%, and the CNT concentration of 0.005 wt.%, the tissue burst pressure strength reaches 56.2 mmHg.
