The need for standardization and improved open (meta)data practices in metaproteomics
Tim Van Den Bossche1,2, Maximilian Wolf3,4, Jean Armengaud5
1CompOmics, VIB-UGent Center for Medical Biotechnology, Ghent, Belgium.
Microbiome
|July 23, 2026
Summary
Standardizing metaproteomics workflows is crucial for reproducible microbial community analysis. This study introduces a reporting checklist and metadata practices to enhance data integration and FAIR compliance.
Area of Science:
- Microbiology
- Proteomics
- Bioinformatics
Background:
- Metaproteomics offers functional insights into microbial communities.
- Current workflows lack standardization, hindering reproducibility and data integration.
Purpose of the Study:
- To develop a community-endorsed reporting checklist for metaproteomics.
- To outline strategies for structured and interoperable metadata capture.
Main Methods:
- Community development of a reporting checklist.
- Leveraging existing standards from proteomics and microbiome research.
Main Results:
- A tailored reporting checklist for metaproteomics was created.
- Efforts to enable structured metadata capture were outlined.
Conclusions:
- Transparent reporting and advanced metadata practices improve metaproteomics reproducibility.
- Recommendations align metaproteomics with FAIR principles for interoperable research.
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