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Published on: January 26, 2019
Respiratory Syncytial Virus Immunization Intention During Pregnancy and Infancy
Rachael M Porter1, Ilse Campos1, Mohammed Shoaib1
1Hubert Department of Global Health, Rollins School of Public Health, Emory University, Atlanta, Georgia.
JAMA Network Open
|July 24, 2026
Summary
Maternal vaccination during pregnancy is preferred for infant protection against respiratory syncytial virus (RSV). Healthcare provider recommendations significantly influence immunization acceptance for both maternal and infant RSV vaccines.
Area of Science:
- Immunology
- Public Health
- Pediatrics
Background:
- Respiratory syncytial virus (RSV) is a primary cause of infant hospitalizations in the US.
- Two main immunization strategies exist: maternal vaccination during pregnancy and RSV antibody shots for infants post-birth.
- Current immunization coverage gaps highlight missed opportunities for infant protection against RSV.
Purpose of the Study:
- To assess RSV immunization intentions, behaviors, and preferences among pregnant women and parents of young children (aged 0-5 years).
- To understand factors influencing decisions regarding maternal RSV vaccination and infant RSV antibody shots.
Main Methods:
- Two national cross-sectional surveys were conducted in April 2024 with US adults who were pregnant or parents of young children.
- Participants were recruited via a representative online survey panel.
- Data from 1765 parents and 174 pregnant women were analyzed.
Main Results:
- Over 55% of pregnant women and 60% of parents showed positive intention towards RSV immunization for their child.
- Maternal vaccination was preferred over infant antibody shots by both groups (58.2% pregnant women, 48.3% parents).
- Lack of information and safety concerns were key reasons for hesitancy, though strong healthcare provider recommendations increased acceptance.
Conclusions:
- Pregnant women and parents show a preference for maternal RSV vaccination for infant protection.
- Healthcare provider recommendations play a crucial role in overcoming hesitancy and increasing immunization acceptance.
- Future strategies should focus on improved communication about RSV immunization options and reinforcing healthcare provider endorsements.
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