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Gene Regulation and Targeted Therapy in Gastric Cancer Peritoneal Metastasis: Radiological Findings from Dual Energy CT and PET/CT
Published on: January 22, 2018
FDG PET/CT in Immuno-Oncology
Lekshmanan Sisily Sanjith1, Bangkim Chandra Khangembam1, Rakesh Kumar1
1Department of Nuclear Medicine, All India Institute of Medical Sciences, New Delhi - 110029, India.
Abstract:
18F-fluorodeoxyglucose PET-computed tomography (FDG PET/CT) is the current standard metabolic imaging method for cancer diagnosis, staging, and treatment monitoring, as it tracks the uptake and phosphorylation of the nonmetabolizable glucose analogue fluorodeoxyglucose. It occupies a pivotal role in the management of patients with cancer receiving immunotherapy. This article examines the multidimensional applications of FDG PET/CT in immuno-oncology, that is, the tumor immune microenvironment, baseline staging, response assessment, identification of immune-related adverse events, and prediction of immunotherapy response. A detailed understanding of FDG PET/CT in this context is essential for optimal patient management.
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