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Chest compression synchronized ventilation versus chest compression asynchronized ventilation in asphyxiated
Shrieya Praveen1, Megan O'Reilly1,2, Raza Hyderi1
1Centre for the Studies of Asphyxia and Resuscitation, Neonatal Research Unit, Royal Alexandra Hospital, Edmonton, AB, Canada.
Chest compression synchronized ventilation (CCSV) did not improve return of spontaneous circulation (ROSC) in piglets compared to asynchronous ventilation (CCaV). This study found no significant difference in ROSC time or rates between the two ventilation methods.
Area of Science:
- Pediatric Resuscitation
- Cardiopulmonary Physiology
- Emergency Medicine
Background:
- Current pediatric guidelines advocate for chest compressions with asynchronous ventilation (CCaV) post-advanced airway placement.
- Chest compression synchronized ventilation (CCSV) presents a potential alternative approach.
Purpose of the Study:
- To investigate if CCSV decreases the time to return of spontaneous circulation (ROSC) compared to CCaV in asphyxiated pediatric piglets experiencing bradycardic cardiac arrest.
Main Methods:
- Twenty pediatric piglets (3-4 weeks old) underwent induced asphyxia and cardiac arrest.
- Piglets were randomized to either CCSV (ventilations synchronized with compressions) or CCaV (asynchronous ventilations).
- Resuscitation continued until ROSC was achieved.
Main Results:
- No significant difference in asphyxia time between CCSV and CCaV groups.
- Time to ROSC was not significantly different (CCSV: 428s vs. CCaV: 271s; p=0.240).
- ROSC rates were identical (6/10) in both groups.
Conclusions:
- CCSV, despite higher ventilation rates, did not improve ROSC outcomes in pediatric piglets compared to CCaV.
- Hemodynamic parameters and lung inflammation markers were comparable, suggesting no added pulmonary injury with CCSV.
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