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Updated: Aug 6, 2026

Measurement of Factor V Activity in Human Plasma Using a Microplate Coagulation Assay
Published on: September 9, 2012
DIEP reconstruction in a patient with Factor V Leiden deficiency: A case report and literature review
Olivia Quinn1, Sumbal Bhatti1, Anais Rosich-Medina1
1Department of Plastic and Reconstructive Surgery, Norfolk and Norwich University Hospital, Norwich, UK.
Abstract:
We report a 63-year-old female with Factor V Leiden deficiency who underwent a left delayed DIEP flap reconstruction with contralateral symmetrising breast reduction following mastectomy. Hypercoagulable disorders are theorised to increase flap failure risk. Current evidence and operative guidance are limited. A focused review of the literature is provided.
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