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Persistent Food Insecurity and Overweight/Obesity Risk in Offspring of Individuals With Gestational Diabetes
Keally Haushalter1, Jaimie N Davis1, Yeyi Zhu2,3
1Department of Nutritional Sciences, University of Texas at Austin, Austin, Texas, USA.
Insights
Persistent food insecurity in early childhood significantly increases the risk of overweight, obesity, and severe obesity in children born to mothers with gestational diabetes mellitus (GDM). Early screening for food insecurity is crucial for identifying at-risk youth.
Area of Science:
- Pediatric Endocrinology
- Public Health Nutrition
- Maternal-Fetal Medicine
Background:
- Gestational diabetes mellitus (GDM) in mothers poses risks for offspring's long-term health.
- Early life food insecurity is a potential environmental factor influencing childhood obesity.
- Understanding the interplay between GDM exposure and food insecurity is critical for preventative strategies.
Purpose of the Study:
- To investigate the association between varying levels of food insecurity during the first two years of life and the prevalence of overweight and obesity in children aged 6-11 years.
- To specifically examine this relationship in children born to mothers with a history of GDM.
- To identify potential targets for intervention to mitigate obesity risk in this vulnerable population.
Main Methods:
- Secondary analysis of a prospective cohort study involving 1033 mother-child dyads.
- Food insecurity was assessed at multiple time points: 6-9 weeks, 1 year, and 2 years postpartum.
- Children were categorized into persistent food security, persistent food insecurity, and transient food insecurity groups. Overweight, obesity, and severe obesity were determined at 6-11 years using BMI percentiles. Statistical analyses included linear and logistic regressions.
Main Results:
- The study included 748 children, with 72% experiencing persistent food security, 18% transient food insecurity, and 10% persistent food insecurity.
- Children with persistent food insecurity showed significantly higher odds of being overweight (aOR=2.81), obese (aOR=2.17), and severely obese (aOR=2.62) compared to those with persistent food security.
- These associations remained significant (p < 0.05), highlighting a strong link between early life food insecurity and later obesity in this cohort.
Conclusions:
- Persistent food insecurity in the first two years of life is a significant risk factor for overweight, obesity, and severe obesity in children born to mothers with GDM.
- Screening for and addressing food insecurity in early childhood is a vital strategy for identifying and supporting children at elevated risk.
- Interventions targeting food insecurity may play a key role in preventing childhood obesity within GDM-exposed populations.
Objective:
Assess how changes in food insecurity in the first 2 years of life are associated with overweight and obesity among children 6-11 years old born to mothers with gestational diabetes mellitus (GDM).
Methods:
This secondary analysis utilised data from the Study of Women, Infant Feeding and Type 2 Diabetes Mellitus after GDM pregnancy, a prospective cohort of 1033 mother-child dyads. Food insecurity was assessed 6-9 weeks, 1 year and 2 years postpartum. Children were categorized as having persistent food security (food secure all visits), persistent food insecurity (food insecure all visits), or transient food insecurity (experienced both food security and insecurity). Overweight, obesity and severe obesity were classified using height and weight at 6-11 years old. Linear and logistic regressions estimated the relationship between food insecurity groups and BMI percentile, overweight, obesity and severe obesity.
Results:
Among 748 youth, 72% had persistent food security, 18% had transient food insecurity and 10% had persistent food insecurity. Compared to those with persistent food security, those with persistent food insecurity had higher odds of overweight (aOR = 2.81, [1.36, 5.80]), obesity (aOR = 2.17, [1.05, 4.47]) and severe obesity (aOR = 2.62, [1.02, 6.74]) (p < 0.05).
Conclusions:
Screening and addressing food insecurity during early childhood may help identify children at risk for overweight, obesity and severe obesity among children exposed to GDM.
Trial Registration:
ClinicalTrials.gov identifier: NCT019967030.
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