Related Experiment Video

Updated: Aug 5, 2026

Cutaneous Leishmaniasis in the Dorsal Skin of Hamsters: a Useful Model for the Screening of Antileishmanial Drugs
11:36

Cutaneous Leishmaniasis in the Dorsal Skin of Hamsters: a Useful Model for the Screening of Antileishmanial Drugs

Published on: April 21, 2012

Frequency, Demographic and Clinical Characteristics of Pediatric Lophomoniasis: A Cross-Sectional Study in Northern

Mahdi Mazandarani1,2, Raeen Ahani Azari3, Mohammad Hadi Tajik Jalayeri1

  • 1Clinical Research Development Unit (CRDU), Sayyad Shirazi Hospital, Golestan University of Medical Sciences, Gorgan, Iran.

Pediatric Pulmonology
|July 27, 2026
PubMed

Insights

Lophomoniasis is a common respiratory infection in children with chronic symptoms, often linked to underlying diseases. Early diagnosis via bronchoscopy with bronchoalveolar lavage (BAL) is crucial for this vulnerable group.

Area of Science:

  • Pediatric Pulmonology
  • Infectious Diseases
  • Microbiology

Background:

  • Lophomoniasis is an emerging respiratory infection with poorly defined pediatric characteristics.
  • Understanding its prevalence and features in children is essential for effective management.

Purpose of the Study:

  • To determine the prevalence of lophomoniasis in children admitted to a pediatric respiratory referral center.
  • To describe the clinical, radiological, and bronchoscopic features of pediatric lophomoniasis.

Main Methods:

  • A cross-sectional study involving 121 pediatric patients with persistent respiratory symptoms.
  • Diagnosis of lophomoniasis was confirmed using bronchoalveolar lavage (BAL) samples.

Main Results:

  • Lophomoniasis was diagnosed in 18.1% of pediatric patients.
  • Common symptoms included cough, fever, and sputum; radiographic consolidation and increased bronchial wall thickness were frequent findings.
  • Lophomoniasis showed a significant association with underlying diseases (p=0.001), anemia, and positive CRP levels.

Conclusions:

  • Lophomoniasis is a frequent diagnosis in children with chronic respiratory issues needing bronchoscopy.
  • The strong association with underlying respiratory conditions necessitates systematic screening in high-risk pediatric populations.
  • Bronchoscopy with BAL is a valuable diagnostic method for lophomoniasis, especially with suggestive clinical and radiological signs.
Abstract

Keywords:
lophomonasparasitepediatricsprevalencepulmonary diseases

More Related Videos

In Vivo Imaging of Leishmania infantum-infected Hamsters by Gingival Inoculation of Axenic Amastigotes Expressing Luciferase05:55

In Vivo Imaging of Leishmania infantum-infected Hamsters by Gingival Inoculation of Axenic Amastigotes Expressing Luciferase

Published on: April 4, 2025

Related Concept Videos

Leishmaniasis01:30

Leishmaniasis

Leishmaniasis is a protozoal disease caused by species of the genus Leishmania and transmitted through the bite of infected female sandflies. The parasite exists in two principal morphological forms during its life cycle. A sandfly acquires intracellular amastigotes from an infected reservoir host, such as a dog. Within the sandfly, these forms differentiate into motile, flagellated promastigotes. During a subsequent blood meal, promastigotes are injected into the human host, where they...
Fungal Phylum Microsporidia01:28

Fungal Phylum Microsporidia

Microsporidia are a group of obligate intracellular fungi that were initially classified as protists but were later reclassified based on phylogenetic, molecular, and structural evidence linking them to the Chytridiomycota. These unicellular, non-motile organisms are highly specialized parasites that infect a wide range of animal hosts, including humans. They have evolved extensive genomic and metabolic reductions, making them highly dependent on their hosts for survival.Morphology and Genomic...
Toxoplasmosis01:28

Toxoplasmosis

Toxoplasmosis, a zoonotic disease caused by the protozoan Toxoplasma gondii, poses significant public health challenges globally due to its high seroprevalence and varied clinical manifestations. As an obligate intracellular parasite, T. gondii can infect all warm-blooded vertebrates, but felids are its only definitive hosts, shedding unsporulated oocysts into the environment. Humans typically acquire the infection through ingestion of tissue cysts in undercooked meat or oocysts from...