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MSCF-Net: A Vision Mamba Network with Multi-Scale Context Bridging and Cross-Layer Adaptive Fusion for Medical Image
Jiahao Guo1, Tao Chen1, Jiaxi Hu1
1School of Mathematics and Computer Science, Shaanxi University of Technology, Hanzhong 723001, China.
Journal of Imaging
|July 27, 2026
Summary
This study introduces MSCF-Net, a Vision Mamba segmentation network that enhances medical image analysis by improving local context and feature fusion. MSCF-Net achieves competitive segmentation performance for dermoscopic and endoscopic images.
Area of Science:
- Medical Image Analysis
- Computer Vision
- Deep Learning
Background:
- Accurate medical image segmentation is difficult due to lesion variations and background interference.
- Existing Mamba-based U-Net models struggle with local multi-scale representation and skip connections.
Purpose of the Study:
- To propose MSCF-Net, a novel Vision Mamba segmentation network for improved dermoscopic and endoscopic image analysis.
- To address limitations in local context and feature fusion in Mamba-based segmentation networks.
Main Methods:
- Developed MSCF-Net, a Vision Mamba network built upon VM-UNet.
- Introduced Multi-Scale Context Bridging (MSCB) to enrich bottleneck features with diverse context.
- Implemented Cross-Layer Adaptive Fusion (CLAF) for adaptive recalibration of encoder-decoder features.
- Utilized a structure loss to enhance region completeness and boundary quality.
Main Results:
- MSCF-Net achieved high performance on benchmark datasets (ISIC 2017, ISIC 2018, CVC-ClinicDB) with Dice scores up to 91.72% and mIoU up to 84.56%.
- Demonstrated competitive segmentation accuracy compared to existing methods.
- Ablation studies confirmed MSCB's role in scale-aware representation and CLAF's effectiveness in focusing on lesion cues.
Conclusions:
- MSCF-Net offers a favorable accuracy-efficiency trade-off for medical image segmentation.
- The proposed MSCB and CLAF modules significantly improve segmentation quality.
- MSCF-Net shows promise for clinical applications requiring precise medical image segmentation.