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Anatomical Rationale for Motor Endplate Zone-Targeted Botulinum Toxin Injection in the Masseter Muscle: A

Kazuya Yoshida1

  • 1Department of Oral and Maxillofacial Surgery, National Hospital Organization, Kyoto Medical Center, 1-1 Mukaihata-cho, Fukakusa, Fushimi-ku, Kyoto 612-8555, Japan.

Toxins
|July 27, 2026
PubMed
Summary

Targeting motor endplate zones (MEZs) for botulinum neurotoxin (BoNT) injections may improve masseter muscle treatment. This approach aims for efficient blockade with potentially lower doses, reducing adverse events in conditions like bruxism.

Keywords:
adverse effectsbotulinum toxinbruxisminjection techniquemasseter musclemotor endplate zonetemporomandibular disorders

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