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Published on: July 26, 2017
From Modified Haller Index to a Novel Patented Anatomical Measurement Device: Engineering Development, Validation,
Andrea Sonaglioni1, Gian Luigi Nicolosi2, Massimo Baravelli1
1Division of Cardiology, IRCCS MultiMedica, 20123 Milan, Italy.
Bioengineering (Basel, Switzerland)
|July 28, 2026
Summary
The Modified Haller Index (MHI) offers a non-invasive method to assess thoracic morphology, crucial for understanding cardiopulmonary health. A new device standardizes MHI measurements for easier clinical use.
Area of Science:
- Cardiovascular Medicine
- Respiratory Physiology
- Medical Imaging
Background:
- Thoracic morphology significantly impacts cardiopulmonary function and diagnostic imaging.
- The traditional Haller Index (HI) for pectus excavatum requires CT scans and radiation, limiting its use.
- The Modified Haller Index (MHI) was developed as a non-invasive, radiation-free alternative using anthropometry and echocardiography.
Purpose of the Study:
- To review the evolution of thoracic morphometry and the clinical validation of the MHI.
- To introduce a novel patented device for standardized, radiation-free thoracic MHI measurements.
- To highlight the growing evidence on thoracic conformation's clinical significance in cardiovascular and respiratory medicine.
Main Methods:
- Review of historical data and clinical validation studies of the MHI.
- Description of a newly engineered, patented anatomical measurement device for thoracic morphometry.
- Synthesis of evidence linking thoracic morphology to cardiopulmonary phenotypes.
Main Results:
- The MHI is a validated, radiation-free tool for assessing thoracic morphology and its cardiopulmonary impact.
- A novel device standardizes MHI measurements, improving reproducibility and bedside application.
- Elevated MHI values correlate with specific cardiopulmonary phenotypes, including reduced thoracic diameter and altered cardiac/pulmonary function.
Conclusions:
- The MHI and the new measurement device provide a practical platform for standardized, radiation-free thoracic phenotyping.
- Thoracic morphology is a clinically relevant factor across cardiovascular and respiratory diseases.
- Future integration with digital technologies promises advanced digital thoracic phenotyping for precision medicine.

