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Published on: September 16, 2021
Spontaneous Conception in Couples Who Need Assisted Reproduction Technology Treatment-A Narrative Review
Izhar Ben Shlomo1, Dikla Kamisa2,3, Vardi Benesh Raviv1
1The Program for Emergency Medicine, Zefat Academic College, Safed 1320611, Israel.
Medicina (Kaunas, Lithuania)
|July 28, 2026
Summary
Unexpected natural conception can occur in various scenarios during or after assisted reproductive technology (ART) treatments. Couples should be informed about these chances, ranging from 2-25%, to aid treatment decisions.
Area of Science:
- Reproductive Medicine
- Infertility Research
Background:
- Many couples pursue assisted reproductive technology (ART) after experiencing infertility or failed treatments like intrauterine insemination (IUI).
- Spontaneous conception following ART, successful or not, can be unexpected for couples.
Purpose of the Study:
- To review scenarios of spontaneous conception occurring around ART.
- To determine the likelihood of spontaneous conception in these scenarios.
Main Methods:
- Literature search on PubMed using terms 'spontaneous conception' and 'ART' or 'IVF'.
- Manual cross-referencing to ensure comprehensive literature retrieval.
Main Results:
- Spontaneous conceptions occur before ART initiation, between cycles, after ART failure, and after successful ART.
- Factors influencing spontaneous conception include waiting time, treatment gaps, cost, age, infertility duration, and cause.
- Chances range from 2% to 25%, with female age and male factor impacting rates.
Conclusions:
- Couples undergoing ART should be informed about the possibility of spontaneous conception.
- This information can guide decisions about starting, continuing, or discontinuing fertility treatments.
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