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Inclusion Membrane Proteins of Chlamydia trachomatis: A Review with Emphasis on Biological Functions and Host Cell
Yujia Guo1, Jie Xiao1, Bingbing Su1
1Institute of Pathogenic Biology, Hengyang Medical College, University of South China, Hengyang 421001, China.
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Chlamydia trachomatis is an obligate intracellular prokaryote. During the process of infecting host cells, C. trachomatis forms a unique inclusion structure, which serves as a critical niche for the survival and replication of C. trachomatis within host cells. The inclusion membrane is composed of various inclusion membrane proteins (Inc proteins), which play a pivotal role in the interaction between C. trachomatis and host cells. This review illustrates functional research progress of C. trachomatis Inc proteins and their molecular interactions with host cells, facilitating deeper understanding of chlamydial pathogenic mechanisms.
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