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Updated: Aug 5, 2026

Robot-Assisted Laparoscopic Splenectomy In Children: A Case Report with Literature Review
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Fatal Delayed-Onset Overwhelming Post-splenectomy Infection 26 Years After Splenectomy for Immune Thrombocytopenic

David Ramzy1, Rouba Isshak1, Katrina Villegas1

  • 1Internal Medicine, St. Joseph's Regional Medical Center, Paterson, USA.

Cureus
|July 28, 2026
PubMed
Summary

Overwhelming post-splenectomy infection (OPSI) is a rare but deadly complication. This case highlights the severe risks of OPSI, even decades after splenectomy, emphasizing prompt diagnosis and treatment for asplenic patients.

Keywords:
aspleniadisseminated intravascular coagulationencapsulated organismsimmune thrombocytopenic purpuraopsioverwhelming post-splenectomy infectionpneumococcal vaccinationpurpura fulminansseptic shockstreptococcus pneumoniae

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