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Updated: Aug 5, 2026

The Pocket-Creation Procedure of Endoscopic Submucosal Dissection for Large Rectal Laterally Spreading Tumors
Published on: February 13, 2026
Large Rectal Neuroendocrine Tumor Curatively Resected Using Loop Ligation Device
Lauren Matlack1, Sherifatu Abu1, Shruti Sirapu1
1Department of Gastroenterology and Hepatology, Temple University Hospital, Philadelphia, Pennsylvania.
Abstract:
Rectal neuroendocrine tumors (NETs) account for a small portion of all rectal neoplasms, however, encompass approximately 20% of all NETs arising from the gastrointestinal tract or pancreas. Band ligation with hot en bloc endoscopic mucosal resection (EMR) is highly effective and frequently used for resection of smaller NETs. We present a case of a NET that was unable to be resected by standard EMR and endoscopic full-thickness resection due to size, or endoscopic submucosal dissection given complexity, time, cost, and complication rates, and was resected using underwater EMR technique with a loop ligation device and hot snare.
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